added to acamedia cache on July 25, 2005

Figure 1-8: Cellular and Humoral Immunity

Overview of the humoral and cell-mediated branches of the immune system. The humoral response involves interaction of B cells with antigen (Ag) and their differentiation into antibody-secreting plasma cells. The secreted antibody (Ab) binds to the antigen and facilitates its clearance from the body. The cell-mediated responses involve various subpopulations of T cells that recognize antigen presented on self-cells. TH cells respond to antigen by producing cytokines. TC cells respond to antigen by developing into cytotoxic T lymphocytes (CTLs), which mediate killing of altered self-cells (e.g., virus-infected cells).


© 1997, Duane W. Sears


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W. H. Freeman & Co. and Sumanas, Inc.
Immunology, January, 1997