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Immune Response: Analysis and Modeling in Neuroborreliosis Immunantwort: Bestimmung, mathematisches Modell und Auswertung zur Steuerung der Therapie einer Neuroborreliose   Google Advanced Scholar Search Scholar Help       Immune Response Modeling (Joachim Gruber) Overview Burrascano's Guidelines and Immune Response Modeling Evaluation of the Long-Term Inflammation in Neuroborreliosis: Duration of Therapy (10. November 2003) Posts in sci.med.diseases.lyme Discussion Paper A Tentative Interpretation of Lyme Flare Cycles and a Corresponding Therapy (April 10, 2004) Analysis Lyme Disease: Statistical Evaluation of a Symptom Log and an Empirical Theory of Flare Cycles (January 3, 2005) Literature Mathematical Model Compartment Models Displaying Lyme Disease Symptom Cycles (Sept., 2003) Background Material Generalized niches: a tentative definition (August 28, 2004 ) Niches protect Borelia burgdorferi (Bb) from the immune system or the antibiotic or render toxin released by Bb "invisible" to the immune system. The protection may wane with time and so will the size of the spirochete population or toxin inventory within the niche. are provided by the host in the form of body compartments, but can also be produced by Bb itself in the form of chemical or microbiological defense mechanisms. Medical Literature Mechanisms of Inflammation - Immune Response, A Medline Search (February 3, 1999) Intracellular Locations of Borrelia burgdorferi, A Medline Search (February 3, 1999) Mechanisms of Borrelia burgdorferi Invasion into Tissue, A Medline Search (February 3, 1999) more Pharmaco-kinetics and -dynamics Pharmacokinetics: Cefepime Model (December 17, 1998) Pharmacodynamics: Critique of the Minimum Inhibitory Concentration Concept, (January 27, 2004) Computer Programs Mathematica programs (March 15, 2005) used for statistical analysis of symptom log to find symptoms cycles simulation of dynamic immune system reponse ("Immune System Compartment Model", Pharmacodynamics) Case specific information Liegner KB, Health Report: Anamnese / History - Beschwerden / Chief Complaints -  Laborergebnisse / Befunde - Vorbehandlungen / Previous Treatment - Impression - Past Medical History / Familiy History - Physical Examination (Neurological), (March 28, 2004) What we did (March 20, 2001)